Abstract The serendipitous sun lite 250w 250v socket discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are currently considered groundb
Botulism is a potentially fatal intoxication caused by botulinum neurotoxins (BoNTs) produced mainly by Clostridium botulinum.Vaccination against BoNT serotypes C and D is the main procedure to control cattle botulism.Current vaccines contain formaldehyde-inactivated native BoNTs, which have a time-consuming production process and pose safety risks
Protein methyl transferases play critical roles in numerous regulatory pathways that underlie cancer development, progression and therapy-response.Here we discuss the function of PRMT5, a member of the nine-member PRMT family, in controlling oncogenic processes including tumor intrinsic, as well as p32 can opener extrinsic microenvironmental signal
The development of the ovule and the embryo sac of five of the 17 species of Lycium and of one hybrid, recorded for southern Africa, was investigated.All specimens of four of the species and the hybrid (between a hermaphroditic and a functionally dioecious species) were found to be functionally dioecious: they express only one sex, although both ma
Abstract Vaccine hesitancy is a major global challenge facing COVID-19 immunization programs.Its main source is low public trust in the safety and effectiveness of the vaccine.In a preregistered experimental study, we investigated how using a foreign language when communicating COVID-19 vaccine information influences vaccine acceptance.Hong Kong Ch